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- Diuretics (water retention relievers)
- Drinking too much alcohol
- Genetics (inherited tendencies)
- Hypothyroidism (underactive thyroid)
- Immune-suppressing drugs
- Niacin, or vitamin B-3
- Obesity
- Psoriasis
- Purine-rich diet — liver, game meat, anchovies, sardines, gravy, dried beans and peas, mushrooms, and other foods
- Renal insufficiency (inability of the kidneys to filter waste)
- Tumor lysis syndrome (a rapid release of cells into the blood caused by certain cancers or by chemotherapy for those cancers)”
