-Hemolytic Disease- the breakdown of red blood cells
-Erythroblastosis Fetalis- producing immature red blood cells, in the fetus.

This occurs when the fetus or the fathers’ blood type is incompatible with that of the mothers (i.e.. typically the mother being RH-negative and the father RH-positive).

The mother is to receive an injection called RhoGAm or Rho (D) which is a sterile solution (made from human blood plasma) at 28 weeks of gestation and within 72 hours after birth to avoid the development of antibodies from the mother towards the fetus (an allergic reaction could be possible). The injection works like a vaccine, it contains RH-positive blood, the mothers’ body then detects these antibodies and reacts as though the immune system had already taken action against the “foreign” Rh-positive red blood cells. Therefore distracting the mothers’ immune system from attacking the fetus.